Advanced Methacrylated Gelatin (GelMA) Hydrogel Scaffolds for Wound Care Applications

Caio Athayde de Oliva; Arthur João Reis Lima Rodovalho; Willams Teles Barbosa; Ana Paula Bispo Gonçalves; Jaqueline Leite Vieira; Milena Botelho Pereira Soares; Josiane Dantas Viana Barbosa

doi:10.34178/jbth.v7i2.380

Caio Athayde de Oliva
Arthur João Reis Lima Rodovalho
Willams Teles Barbosa
Ana Paula Bispo Gonçalves
Jaqueline Leite Vieira
Milena Botelho Pereira Soares
Josiane Dantas Viana Barbosa

DOI: https://doi.org/10.34178/jbth.v7i2.380

Resumo

Tissue engineering is an area of research that has been advancing with the implementation of new technologies to create scaffolds that can aid in regenerating damaged tissues. Among these technologies, bioprinting has gained prominence due to the diverse range of hydrogels that can be used as scaffolds and dressings for tissue regeneration. Gelatin methacrylate (GelMA) has been studied for its potential use as a dressing for skin regeneration. This study aimed to evaluate the properties of scaffolds with different concentrations of 3D-printed GelMA for application as wound dressings. The degradation rate and tensile strength of these scaffolds were assessed. Results showed that with increasing GelMA concentration, there was a decrease in the degradation rate and swelling while the maximum tensile stress increased. The next phase of this study will involve incorporating drugs to evaluate their influence on the properties of the scaffolds.